INHERITED NERVOUS SYSTEM DISORDERS
Many nervous system disorders affect both dogs and people. For this reason there tends be more information available about these diseases, than about some of the other, more common, inherited disorders in dogs.
There is some overlap with disorders of the musculoskeletal system. These diseases may also be called metabolic disorders.
Cerebellar abiotrophy (ataxia)
Cervical vertebral instability (Wobbler syndrome)
Congenital deafness and vestibular disease
Hypo-/dysmyelinogenesis ("shaking pup")
Leukodystrophies Rottweiler leukoencephalomyelopathy, Dalmatian leukodystrophy, miniature poodle demyelinating myelopathy, hereditary ataxia, hound ataxia, Labrador retriever central axonopathy, Afghan myelomalacia, spongiform leukodystrophy, fibrinoid leukodystrophy
Lysosomal storage diseases ceroid lipofuscinosis, fucosidosis, glucocerebrosidosis, glycogen storage disease type III, GM1 gangliosidosis, GM2 gangliosidosis, mucopolysaccharidosis I, sphingomyelinosis
Meningitis Beagle pain syndrome, Bernese mountain dog aseptic meningitis, pug meningoencephalitis
Myelodysplasia (spinal dysraphism)
Peripheral neuropathies Dancing Doberman disease, Rottweiler distal polyneuropathy, giant axonal neuropathy, idiopathic polyneuropathy (Alaskan malamute), hypertrophic neuropathy, boxer progressive axonopathy, sensory neuropathy, laryngeal paralysis -polyneuropathy complex (dalmatian) Megaesophagus is a common complication in several breeds.
Spinal muscular atrophy / motor neuron diseases Spinal muscular atrophy (Brittany spaniel), focal spinal muscular atrophy (German shepherd), hereditary progressive spinal muscular atrophy (English pointer), motor neuron disease (rottweiler), multisystemic chromatolytic neuronal degeneration (Cairn terrier)
Vertebral stenosis (associated with cauda equina syndrome)
Copyright © 1998 Canine Inherited Disorders Database. All rights reserved.
Revised:July 12, 2004.