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Individual Problems.
Although we do not have the capacity to address individual problems in any great detail during the course (mainly due to its popularity), participants will learn the most if they bring with them at least the ideas for a particular infectious disease of which they have some experience.
Literature
In addition to the references and suggestions for further reading made throughout the course, we will supply the following references to the participants either within the course notes or in electronic format (Adobe Acrobat files):
The first three references are supplied in the course notes and form the bulk of the lectures on the logic and consequences of vaccination:
- Anderson RM and Nokes DJ (1991) Mathematical models of transmission and control. In Oxford Textbook of Public Health Volume 2, Chapter 14 (Holland WW, Detels R and Knox G, editors), Oxford Medical Publications, 2nd Edition, 1991.
- Nokes DJ and Anderson RM (1992) Mathematical models of infectious agent transmission and the impact of mass vaccination. Reviews in Medical Microbiology. Volume 3; Pages 187-195.
- Nokes DJ and Anderson RM (1993) Application of mathematical models to the design of immunisation strategies. Reviews in Medical Microbiology. Volume 4; Pages 1-7.
Material from the following three references (available as pdf files) will be presented as a veterinary example of modelling an infection of "known" biology from exploration of basic principals through control policy design to economic analysis of impact:
- O'Callaghan CJ, Medley GF, Peter TF and Perry BD. (1998) Investigating the epidemiology of heartwater (Cowdria ruminantium infection) by means of a transmission dynamics model. Parasitology Volume 117; Issue 1; Pages 49-61.
- Callaghan CJ, Medley GF, Peter TF, Mahan SM and Perry BD. (1999) The effect of vaccination on the transmission dynamics of heartwater (Cowdria ruminantium infection). Preventive Veterinary Medicine Volume 42; Issue 1; Pages 17-39.
- Mukhebi AW, Chamboko T, O'Callaghan CJ, Peter TF, Kruska RL, Medley GF, Mahan SM and Perry BD. (1999) An assessment of the economic impact of Heartwater (Cowdria ruminantium infection) and its control in Zimbabwe. Preventive Veterinary Medicine Volume 39; Issue 3; Pages 173-189.
Two examples of mathematical modelling manuscripts for veterinary pathogens are also presented as pdf files. The first should fall well within the level of understanding of the participants after this course. The second is highly mathematical and well well beyond the level of complexity of the course but is "cutting edge" and we present it as an example of the progress being made in the context of infectious diseases of veterinary importance:
- Cherry BR, Reeves MJ and Smith G. (1998) Evaluation of bovine viral diarrhea virus control using a mathematical model of infection dynamics. Preventive Veterinary Medicine Volume 33; Pages 91-108.
- Greenhalgh D, Diekmann O and de Jong MCM. (2000). Subcritical endemic steady states in mathematical models for animal infections with incomplete immunity. Mathematical Biosciences Volume 165; Issue 1; Pages 1-25.
Additional / Further Reading (at your leisure):
- Anderson & May, Infectious Diseases of Humans: Dynamics & Control. Oxford University Press, 2nd edition, 1991.
- Woolhouse, MEJ, Haydon DT and Bundy DAP. (1997) The design of veterinary vaccination programmes. The Veterinary Journal Volume 153; Pages 41-47.
Software
We will be using ModelMaker Ver. 4.0.1 during the course. It is available for a 30 day free trial from: www.modelkinetix.com You are welcome to bring a disk and copy the examples we give during the course for your own use.
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Atlantic Veterinary College |
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PEI Visitor's Guide |
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Charlottetown |
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Multi-level Modelling |
| Instructors's Home Pages | |
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Graham Medley |
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Henrik Stryhn |