Welcome to the publication list.

Here is a list of the publications of the Linkletter Research Group. They are available in Adobe Acrobat ".PDF" format and an external link is given to the actual journal article on the publisher's web site where applicable.


Refereed Publications

  • Solid-Phase Synthesis of Oligopurine Deoxynucleic Guanidine (DNG) and Analysis of Binding with DNA Oligomers.
    Linkletter, B.; Szabo, I.E.; Bruice. T.C. Nucl. Acids Res. Dec. 2001, 29, 2370-2376
    PDF version Publisher's Site

  • Solid-phase Synthesis of Positively Charged Deoxynucleic Guanidine (DNG) Modified Oligonucleotides Containing Neutral Urea Linkages. Effect of Charge Deletions on Binding and Fidelity.
    Linkletter, B.; Bruice, T.C.. Bioorg. Med. Chem. 2000, 1893-1901.
    PDF version (388 K) Publisher's Site

  • Rapid Hydrolysis of 2’,3’-cAMP with a Cu(II) Complex: Effect of Intramolecular Hydrogen Bonding on the Basicity and Reactivity of a Metal-Bound Hydroxide.
    Wall, W.; Linkletter, B.; Williams, D.; Lebuis, A.-M.; Hynes, R.C.; Chin, J. J. Am. Chem. Soc. 1999, 121, 4710-4711.
    PDF version (48 K) Publisher's Site

  • Solid-Phase Synthesis of Deoxynucleic Guanidine (DNG) Oligomers and Melting Point and Circular Dichroism Analysis of Binding Fidelity of Octameric Thymidyl Oligomers with DNA Oligomers.
    Barry A. Linkletter, Istvan E. Szabo, and Thomas C. Bruice
    Journal of the American Chemical Society, 1999, 121, 3888-96
    PDF version (152 K) Publisher's Site

  • Synthesis of Protected Guanidinium Linked Dinucleoside Incorporable Into an Oligonucleotide Using Solid Phase DNA Methodology.
    Dinesh A. Barawkar, Barry Linkletter, and Thomas C. Bruice
    Bioorganic & Medicinal Chemistry Letters, 1998, 8, 1517-20.
    PDF version (268 K) Publisher's Site

  • Solid-Phase Synthesis of Oligomeric Deoxynucleic Guanidine (DNG): A Polycationic Analogue of DNA.
    Barry A. Linkletter and Thomas C. Bruice
    Bioorganic & Medicinal Chemistry Letters, 1998, 8, 1285-90.
    PDF version (436 K) Publisher's Site

  • Rapid Hydrolysis of RNA with a Cu Complex.
    Linkletter B; Chin J.
    Angewandte Chemie-International Edition In English, 1995, 34, 472-474.

  • Benzylchlorocarbene - UV Absorption Spectrum, Kinetics For 1,2-H Migration and Mechanism For Reaction With Acetic Acid as Determined by Combined Continuous and Laser-Flash Photolysis.
    Bonneau R.; Liu M.T.H.; Subramanian R.; Linkletter B.; et. al..
    Laser Chemistry, 1990, 10, 267-275.


Conference Presentations

  • Solid-Phase Synthesis of Oligopurine Deoxynucleic Guanidine (DNG) and Analysis of Binding with DNA Oligomers. Studies Toward a New Antisense Therapeutic Agent.
    Oral presentation at the 84th Canadian Society for Chemistry Conference & Exhibition, Montreal, Quebec, June 1, 2001
    PDF version (332 K)

  • Deoxynucleic Guanidine (DNG), a positively charged DNA analogue: Effect of modulating the overall positive charge on DNG oligomers upon binding affinity and specificity with complementary and mismatched DNA targets.
    Oral presentation at the 218th American Chemical Society National Meeting,
    New Orleans, Louisiana, August 26, 1999

  • Inclusion of Neutral Urea Linkages in Positively Charged Deoxynucleic Guanidine (DNG) Oligomers. Synthesis and Binding to Complementary DNA.
    Poster presentation at the 81st Canadian Society for Chemistry Conference & Exhibition, Whistler, British Columbia, June 1, 1998

  • Oligomeric deoxyribonucleic guanidine (DNG): A polycationic analogue of DNA. Solid phase synthesis of purine and pyrimidine DNG oligomers and fidelity studies.
    Poster presentation at Cambridge Health Institute’s Oligonucleotide Synthesis Conference, San Francisco, California
    , June 24, 1998